MedGenome Claria https://medgenomeclaria.com MedGenome Claria Wed, 13 Jan 2021 05:24:39 +0000 en-US hourly 1 https://wordpress.org/?v=6.4.3 Carrier Screening Test Process: What to Expect https://medgenomeclaria.com/2018/02/23/carrier-screening-test-process-expect/ https://medgenomeclaria.com/2018/02/23/carrier-screening-test-process-expect/#respond Fri, 23 Feb 2018 18:05:03 +0000 https://medgenomeclaria.com/?p=29296

Couples who are ready to start a family may not be aware that they could be carrying a mutated gene, which could lead to their child developing a genetic disorder like Cystic Fibrosis, Sickle Cell Anemia or Muscular Dystrophy. In most cases, carriers of a genetic abnormality have no signs or symptoms of an underlying problem. Unfortunately, their carrier status is often brought to their attention only after their baby has been conceived, reducing the time and options they have to make a decision. However, with a little planning and a simple blood test, you can determine your chances of having a baby with a genetic condition long before he or she is conceived.

The MedGenome Claria Carrier Screening Test will provide you and your partner with the reassurance you need long before you start planning for your baby.

Carrier Screening Test Process:

Most couples don’t realize just how easy it is to be screened for genetic diseases. With just a simple blood test, you can learn more than ever before about your genetic health, and how it could affect your children down the road.

Step 1 – Talk to Your Doctor About Carrier Screening

At your next visit to your doctor you should talk to them about Carrier Screening. The topic of genetic diseases and getting screened may not come up during routine conversations, unless you mention it. If you are ready to start a family, your doctor can help you decide if Carrier Screening is right for you, at, even if you don’t have a family history of the same.

Once you have consulted your doctor, our Certified Genetic Counsellors will answer any questions you have regarding the tests and walk you through the Carrier Screening Testing Process with Claria.

 Step 2 – Quick and Simple Blood Draw

Your dedicated genetic counsellor will help you find the closest collection center that is convenient for you. If you are unable to make it to a MedGenome Certified Lab for the sample collection, we can also discuss the option of having a professional visit your residence for the collection. All that is required is a small amount of blood (approximately 3-5 ml) withdrawn from the arm and it is sent off to our state-of-the-art facilities at no extra cost.

Step 3 – Receive Your Personalized Results

Unlike other companies, MedGenome Labs performs the entire screening and reporting process within India. Most of the other labs send your blood sample to labs in different countries, where it is compared to those populations’ genetic variations rather than our own population MedGenome’s Carrier Screening Test was developed to identify inherited diseases that are unique to the population of India. Since the test is performed right here in India, you will receive your result much faster and at much lesser cost. It is ensured that you will receive your personalized Carrier Screening report within 4-6 weeks.

Step 4 – Genetic Counseling Before, During and After the Test

At MedGenome Labs, our patients are our priority. We want to help you make the family planning process as easy as possible. Even before you receive your results, our Certified Genetic Counselors are here for you. They will walk you through your queries of what to expect from the test and, they will be  available  after you have received your personalized report, to offer further guidance and help you understand the results and help you make informed reproductive decisions and your options of moving forward.

If you’re ready take the next big step in the family planning process, talk to your doctor or give us a call at 1800 103 7590. We look forward to being there with you every step of the way.

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How Accurate is Genetic Testing During Pregnancy? https://medgenomeclaria.com/2018/01/22/how-accurate-is-genetic-testing-during-pregnancy/ https://medgenomeclaria.com/2018/01/22/how-accurate-is-genetic-testing-during-pregnancy/#respond Mon, 22 Jan 2018 20:39:16 +0000 https://medgenomeclaria.com/?p=29276

Tests just come with the territory when you’re expecting. In addition to the standard tests, like ultrasounds and the glucose screening test, your doctor may recommend the Non-invasive prenatal test (NIPT) to screen for common chromosomal abnormalities that may affect your developing baby.

In India, we are seeing a high prevalence of chromosomal disorders throughout the country – currently 1 baby in every 200 live births is born with a chromosomal abnormality. NIPT is a vital step in helping to reduce the number of cases diagnosed each year, and at MedGenome Claria we have combined accurate, non-invasive screening with personalized genetic counselling to bring expecting parents peace of mind.

However, you may be wondering just how accurate the Claria NIPT is, and if it is a beneficial option for you and your partner.

Over 99% Accurate

One of the most obvious benefits for parents expecting a new bundle of joy is just the accuracy of non-invasive prenatal screening. Due to recent advancements and new technologies in the field of genetics, our NIPT is more than 99% accurate in detecting the most common chromosomal conditions: Down syndrome, Patau syndrome and Edwards Syndrome.

These conditions can affect your baby’s mental and physical development. It is highly advantageous for parents to be able to find these conditions prior to birth, not only to give them time to understand the disorder and to prepare, but it also gives them time to make decisions that are right for their family.

More Pros of Genetic Testing During Pregnancy:

In addition to the accuracy of the test, there are a few additional benefits that make the Claria NIPT appealing for pregnant women and their partners.

No Risks

NIPT is completed with just a simple blood draw. Not only does that mean there are no risks to you or your developing baby, but it also means the test can be done quickly and with no downtime for recovery. Besides the discomfort from the needle, there are also no side effects to screening.

Expert Genetic Counselling

If you’re considering NIPT, we have expert genetic counsellors on hand to help answer all of your questions. They are available before, during and after your test to help you fully understand NIPT test process and to provide reassurance about the procedure.

Screening Vs Diagnostic Test

While non-invasive prenatal screening is highly accurate, it does not definitively determine if your baby will be born with a chromosomal condition. It does, however, provide parents with accurate results that can tell them the chance their baby will have a chromosomal disorder. Depending on the results of your NIPT, your doctor can help you decide if a diagnostic test, like the amniocentesis or chorionic villus sampling, is the next step for you and your family. However, you should be aware that these invasive tests do come with a slight chance of miscarriage.

Genetic Testing Before Pregnancy: Carrier Screening

If you’re planning to get pregnant, you can actually screen for genetic conditions even before you conceive. Couples who are planning to start a family can get tested to find out if they “carry” any genetic abnormalities that could lead to their children developing a genetic condition.

If you and your partner both carry a genetic change for disorders like cystic fibrosis for example, there is a 25% chance your baby will born with the disease. You can find out exactly what your personal risks are with Carrier Screening.

For the moments that matter most in your life, you need clarity not advice. Trust the experts at MedGenomeClaria.

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Prenatal Screening: What are Microdeletions & Why Should We Test for Them https://medgenomeclaria.com/2017/12/14/prenatal-screening-what-are-microdeletions-why-should-we-test-for-them/ https://medgenomeclaria.com/2017/12/14/prenatal-screening-what-are-microdeletions-why-should-we-test-for-them/#respond Thu, 14 Dec 2017 18:48:16 +0000 https://medgenomeclaria.com/?p=29267

Women who are expecting a baby are no strangers to tests. From their first pregnancy test to the baby’s first hearing test after birth, there is a lot to be screened for and even more to be monitored throughout the course of your pregnancy. While chances are your baby will be born happy and healthy, at your first prenatal appointment your doctor should outline the most important tests and their benefits.

One of those tests, the NIPT, is used to screen for common chromosomal conditions such as Down syndrome as early as the 9th week of pregnancy, but a lot of mums-to-be haven’t yet heard of microdeletions or know how to test for them.

What is a Microdeletion?

Everyone has 46 chromosomes. We receive 23 from our mom and the other 23 from our dad. When a small piece of a chromosome is lost, it is known as a microdeletion.

Some may lead to no physical or mental issues at all, but other more severe deletions could have major impact on a baby’s development. Some of the most common microdeletions to be tested for include DiGeorge syndrome, Angelman syndrome, Prader-Willi and Cri-du-chat syndrome.

Most Common Microdeletion – DiGeorge Syndrome

Also known as 22q11.2 deletion syndrome, DiGeorge syndrome is one of the most common microdeletion conditions. For those who are diagnosed, it is found that a small piece of the middle of chromosome 22 has been deleted. The syndrome can occur in about 1 in every 2,000 births – making the occurrence rate similar to Down syndrome.

There are a wide range of signs and symptoms associated with DiGeorge syndrome. Some of the most common include a cleft palate, congenital heart defects, growth delays, distinct facial features, mental health and psychiatric disorders, and issues with breathing or hearing.

Who is More Likely to Have Baby with Microdeletion?

Certain risk factors, including the mother’s age and family history, can play a major role in the development of a fetus. Chromosomal conditions, such as Down syndrome, are more likely to occur in babies who are subjected to these risks. However, that’s not the cases with microdeletions.

This genetic abnormality normally occurs at random. In fact, it is estimated that many people have chromosomes with a microdeletion, it is just not profound enough to affect their development. Fortunately, there are genetic tests available to detect microdeletions such as DiGeorge syndrome.

Microdeletions Tests – How to Detect the Chromosome Condition

In the past, the only way to thoroughly analyze a baby’s DNA to screen for chromosome abnormalities during pregnancy was with chorionic villus sampling (CVS) or an amniocentesis – both of which come with a slight risk of miscarriage.

Now with modern advancements and more precise technology, the non-invasive prenatal test, also referred to as the NIPT, has made it possible for geneticists to closely examine the baby’s DNA that floats throughout the mother’s blood, providing patients with highly-accurate results.

The NIPT, which is taken by pregnant women as early as their 9th week of gestation, poses no risk for the mother or baby. Additionally, it only requires a small blood sample from the mother and results are usually available within 2 weeks. The NIPT tests for five of the most common microdeletions in addition to screening for other common chromosomal abnormalities like Down syndrome.

What if my NIPT Results are Positive?

The NIPT is a screening test, not a diagnostic test. This means that while the NIPT can screen for genetic abnormalities such as microdeletions during your pregnancy, it cannot tell you with 100% certainty that your baby will be born with a chromosomal condition. The test calculates your odds and helps you determine if a diagnostic test is necessary.  If you do receive a positive result, you can take steps now to improve the quality of life for your diagnosed baby and for your family.

A major benefit to screening for genetic abnormalities during pregnancy is the time and empowerment it allows expecting parents. In addition to educating yourselves, you and your partner can set up appointments with medical specialist who will walk you through the syndrome and the therapies your baby is likely to need. Take advantage of microdeletion testing now to better prepare for your future.

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The NIPT Process: What You Need to Know https://medgenomeclaria.com/2017/11/17/the-nipt-process-what-you-need-to-know/ https://medgenomeclaria.com/2017/11/17/the-nipt-process-what-you-need-to-know/#respond Fri, 17 Nov 2017 20:48:46 +0000 https://www.medgenomeclaria.com/?p=29241

At your first prenatal appointment, your doctor will discuss the tests available to monitor the health and development of your baby throughout your pregnancy. Some of these tests, like an ultrasound, are standard in every pregnancy but other tests, including genetic screening, are decided by the patient on a case by case basis.

Non-invasive prenatal testing (NIPT) can determine the chances of your baby being born with a common chromosomal condition such as Down syndrome, with no risk to you or your developing baby. Although it is a newer option, the benefits of the NIPT are quickly making it popular amongst expecting women.

However, since the NIPT is a newer option, there are a few misconceptions about the test. One of those misunderstanding centers around the screening process itself. Most pregnant women don’t realize just how easy and safe the test is. Unlike diagnostic  prenatal tests like the amniocentesis or chorionic villus sampling (CVS), mums-to-be can understand their risks without any harm to their babies.

The NIPT process is easier than you think. Here is what you can expect:

NIPT Process

Step 1:

After discussing the test with your doctor, contact our genetic counsellors who will explain the entire procedure and answer any of your questions, they will assist you in finding the closest collection center to you. If there are no collection centers close by, our counsellors will direct you to a medical professional who can collect your blood sample and ship it to our lab for screening.

Step 2:

A small sample of your blood from your arm will be collected for the test. Besides a small pinch from the needle, there are no risks to worry about.

Step 3:

The blood sample is then sent to our state-of-the-art laboratory in Bangalore. Our geneticists complete the screen by analyzing the fetal DNA on advanced genetic sequencing machines to determine if there are any chromosomal abnormalities. Patients will receive their personalized reports detailing the findings within just 10-15 days, giving you more time to make decisions moving forward.

Step 4:

Your doctor will help you understand your results and answer any questions you may be having about the outcome.

Step 5:

Our certified genetic experts are available before, during and after your test to discuss your available options and what your next step should be.

Who Should be Screened?

Every woman expecting a baby should be screened as per professional society guidelines. As more people are realizing just how easy the test is from start to finish the NIPT is on track to become a standard prenatal test. Being proactive about your baby’s health now will give him or her a better start at life after birth. Though all women should take the steps to ensure their baby is developing normally, there are some cases where it is extremely important to be screened. If you are expecting a baby and  you or your partner have a family history of chromosomal conditions, it is especially recommended that you are screened. It is also recommended if you have had multiple miscarriages, already have a child with a genetic disorder or suffer from one yourself. Additionally, women over 35 should consider the NIPT because they are at a higher risk of having a baby with a chromosomal disorder.

Other Benefits of the NIPT

There are more advantages to non-invasive prenatal screening than just how quickly and easily your baby can be tested from chromosomal abnormalities. You can be screened as early as 9 weeks into your pregnancy, giving you and your partner ample time to explore your options and make decisions regarding your results. It is also over 99% accurate in detecting chromosomal defects which can lead to the development of genetic conditions including Down syndrome, Patau syndrome and Edwards syndrome.

With the help of advanced technology and dedicated genetics, we now have the ability to learn more than ever before about our babies’ genetic health. A simple blood test can provide insights about how they are developing physically, mentally and emotionally, giving us the power to prepare for our futures. Ready to take the first step? Contact one of our genetic counsellors today.

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5 Common Misconceptions Couples Hear about Carrier Screening https://medgenomeclaria.com/2017/10/15/5-common-misconceptions-couples-hear-carrier-screening/ https://medgenomeclaria.com/2017/10/15/5-common-misconceptions-couples-hear-carrier-screening/#respond Sun, 15 Oct 2017 19:39:08 +0000 https://www.medgenomeclaria.com/?p=29233

As you and your partner prepare for pregnancy, carrier screening should be at the top of your pre-conception “to-do” list. Despite no symptoms, you could be carrying an inherited genetic condition and not even know it. These conditions can be passed to your children if both partners carry the same mutated or defective gene.  Carrier screening is used in the family planning process to detect any genetic disorders you and your significant other may be carrying without your knowledge, and to help you understand the risk of passing one of the conditions on to your children.

Fortunately, you can take steps now to prepare for the future by getting screened. With just a simple blood test, you can determine if your baby will be born with a genetic disorder that could affect their physical and mental development.

However, since carrier screening is a new concept for couples wanting to start a family, there are a few misconceptions about the test. We’re here to help you clear up any confusion.

1] Only couples who have a family history of a genetic disorder should be screened

Any couple who is looking to be proactive in the family planning process should be screened to determine if they carry an inherited genetic disease they could pass to their children, even if there is no family history of such a disorder. In addition to your family history playing a major role in your carrier status, there are other factors that make you a candidate for carrier screening.

If you are related to your partner or spouse genetically (consanguinity), you are more likely to have a child with a genetic condition and you should be screened before you plan to conceive. Couples who already have a child with a genetic disorder or those who suffer from a condition themselves will also benefit from carrier screening.

2] Carrier screening is not specific to disorders found in my demographic area

This is true for some screening tests by companies that outsource the testing to labs in different countries throughout the world, but the Claria screening test was developed to scan for inherited genetic diseases that are specific to the Indian population.

The outsourced tests compare your genetic DNA to the population where their lab is located, meaning your results can easily be skewed. With Claria, your blood sample is collected and screened in India, enabling the identification of genetic disorders that are unique to our country.

3] Carrier screening comes with risks

It is easy to steer clear of medical procedures because you are worried about the risks, but with carrier screening, you don’t have any risks to worry about! The test procedure is extremely simple and only requires a small sample of blood to be taken from your arm.

Besides a small pinch from the needle, there is really nothing else to fear when you are screened to determine your carrier status. In addition, you can even avoid the doctor’s office altogether by having a medical professional come directly to you to collect the blood sample. You will then receive your results within 4-6 weeks.

4] Interpreting the results can be confusing

There’s no confusion with Claria. What sets us apart from other companies that offer carrier screening is our use of the industry’s latest advancements in technology, combined with our dedicated genetic counselors who are available to assist you every step of the way. Our expert counsellors will explain the benefits of screening and the test process, and will answer any of your questions before you and your partner get screened (pre-test counseling). Once you have received your results, your genetic counsellor will thoroughly explain your results, as well as your options for moving forward (post test counseling)

5] There are no options for couples who carry the same genetic condition

If you and you partner are screened and it is determined that you are both carriers of the same genetic condition, there is a 25% chance your child will be born with the disorder, a 25% the child will not carry the disease, and a 50% chance the child will be an unaffected carrier – just like his or her parents. If only one parent is found to be a carrier, your children will have no chance of being born with the disorder and a 50% chance they will be unaffected carriers.

You still have options to start a family if it is determined both you and your partner carry a genetic condition. Some couples may make the decision to conceive, regardless of the odds but are mentally prepared to accept the baby with the disorder.  Another option that can be considered is Artificial Reproductive Techniques (ART) eg. In- vitro fertilization (IVF) with donor eggs or sperm. There is also the option of prenatal diagnosis during the third month of pregnancy and opting for selective termination if the fetus is found to be affected by a genetic condition. Some families also take the route of adoption.

What is right for one family, may not be right for another. Our genetic counsellors are available to help you explore your options and help you make informed decisions that are best suited for you and your family.

If you’re ready to get proactive about your family’s health before you conceive, consider carrier screening!

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Pregnant Over 35: Risks and Precautions https://medgenomeclaria.com/2017/09/03/pregnant-over-35-risks-and-precautions/ https://medgenomeclaria.com/2017/09/03/pregnant-over-35-risks-and-precautions/#respond Sun, 03 Sep 2017 20:41:38 +0000 https://www.medgenomeclaria.com/?p=29224

Women have always been told that the longer they wait to get pregnant, the more risks they are subjected to. However, as modern medicine continues to advance and more women are in a position where they are able to wait, a pregnancy after age 34 may not be as risky as we once thought.

Despite what you may have heard, you can have a healthy pregnancy if you are 35 years old or older – you just need to know your risks and take a few extra precautions to ensure both you and your baby are healthy from conception to delivery.

Advanced Maternal Age

Life doesn’t always go as planned. You may have thought you would have been married with kids by the age of 25, but unexpected events often throw life plans off course. Next thing you know, you’re 35 years old, pregnant with your first baby, and your doctor is grouping you in the “advanced maternal age” category. You are not alone, though. More and more women are choosing to focus on their careers and personal goals before embarking on the journey of motherhood.

An expecting woman is classified to be of advanced maternal age when she is 35 or older at the time at of delivery, and while there are risks, they are much more substantial in women 40 and over. Fortunately, there are several ways to reduce your risks and deliver a happy and healthy baby. One of these  include non invasive prenatal screening , a simple, risk free method of testing the baby for genetic dosorders.

What are the Risks of Having a Baby after 35?

Every pregnancy comes with associated risks. For women 35 and older, these risks are more likely and should be discussed thoroughly with your doctor.

Longer to Conceive

As women age, their fertility rates begin to decline, making it harder for them to get pregnant. Women are born with a limited number of eggs, and over time the quantity and quality of their unfertilized eggs continues to decrease. When your egg’s quality is low, it is more likely to take you longer to conceive and you are at a higher risk of having a miscarriage or delivering a baby with a genetic disorder.

Multiples are More of a Possibility

Pregnant women who are 35 or older have a higher chance of having a pregnancy with multiples. This could be for a couple different reasons. The first being as your hormones change with age, your body could release multiple eggs at the same time. Additionally, multiples are more of a possibility because women 35 or older are more likely to seek assistance in getting pregnant.

Increased Risk for Complications

If you are expecting a child and you are 35 or older, you are more likely to experience complications throughout your pregnancy. It is common for older women to develop gestational diabetes, a condition that is the result of their bodies not being able to produce enough insulin. It is also common for women of advanced maternal age to develop high blood pressure, which can be serious and lead to serious conditions such as pre-eclampsia and eclampsia if not addressed. Fortunately, if you have one of these conditions and seek proper medical intervention, it’s still possible to deliver a healthy baby.

Tips to Increase Chances of Having a Healthy Baby after 35

While the thought of having a baby later in life may seem risky, if you are careful and take the right precautions now, chances are you both will be fine.

Preconception appointment

If you and your partner are ready to have a baby, it is a good idea to set up a preconception appointment with your doctor even before you get pregnant. This is especially true if you’re 35 or older. A preconception appointment is the perfect opportunity to discuss your individual risks, concerns and questions about conceiving and pregnancy. Your doctor can also help you increase your chances of conceiving with helpful tips and professional advice.

Prenatal Care

Attending your regular prenatal appointments is extremely important as it gives your doctor ample opportunity to monitor the health of both you and your baby.  Not only will these appointments help give you peace of mind, they will also give you the chance to address any symptoms or concerns that may develop throughout your pregnancy. You can also use these appointments to talk to your doctor about prenatal screening, pregnancy do’s and don’ts and childbirth.

Screen for Chromosomal Conditions

As an older mum, you are more likely to deliver a baby with a chromosomal condition like Down syndrome. Fortunately, there are noninvasive tests that can screen for these conditions and determine your risk as early as your 9th week of pregnancy. The Claria NIPT is India’s most accurate prenatal screening test and can be completed with just a small sample of blood from the mother. Since screening poses no risk to the mother or baby, more women, especially those 35 years old or older, are opting for this test to get the reassurance they need about their pregnancy.

If you’re pregnant over the age of 35, you don’t have to worry. Our expert genetic counsellors are available to walk you through this journey and answer any questions you may be having.

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9 Practical Tips Every Woman Needs for a Healthy Pregnancy https://medgenomeclaria.com/2017/08/03/9-practical-tips-every-woman-needs-healthy-pregnancy/ https://medgenomeclaria.com/2017/08/03/9-practical-tips-every-woman-needs-healthy-pregnancy/#respond Thu, 03 Aug 2017 10:00:29 +0000 https://www.medgenomeclaria.com/?p=29110

Congratulations on your pregnancy! This is an extremely exciting time for you and your partner. Amidst all the excitement, however, there are a few new things you need to consider to be sure your pregnancy is as healthy as possible. From what you’re eating to your birthing plan, here’s are nine tips to ensure your baby is healthy from conception to delivery!

Research Doctors & Birthing Options

Once you know you are pregnant the excitement of a new baby may cause you to make quick decisions. However, when it comes to the health of you and your baby – you need to be sure you are making the right choices about your medical providers and birthing options. Get recommendations from friends who have already had children, and do your research to make sure your doctor is knowledgeable, understanding and helpful – as well as in line with your birthing plan.

There are multiple options available when it comes to giving birth and while many doctors in India are not extremely open to the idea of birth plans, it is still a good idea to make one. After you have decided how you want to give birth, discuss your plan with your doctor and give a copy of it to everyone who will be involved in the delivery.

 Educate Yourself

If this is your first pregnancy, you will ease worries and feel more prepared by educating yourself on what your body will be experiencing over the next nine months and after you deliver. Not only will you help decrease any anxieties about your pregnancy, but you will feel empowered by knowing everything you can about you and your baby. Even for moms who’ve already had children earlier it’s a good idea to brush up on their baby knowledge – things may have changed since you last delivered.

It is recommended to read all the baby books you can, and you and your partner could even take a few childbirth education classes. For those who don’t like to read, or don’t have the time, podcasts and YouTube videos can also be a great source for information. Lastly, you should keep you and your partner’s medical history records, as well as your families.

If there is any cause for concern, you can get a non-invasive prenatal test (NIPT) to determine what your risks are. An NIPT can be performed with just a simple blood test and carries no risk for the mother or baby. It can detect chromosome abnormalities that could lead to the development of a condition like Down syndrome (trisomy 21), Edward’s syndrome (trisomy 18) or Patau syndrome (trisomy 13).

Want the latest pregnancy tips and info? Subscribe to our pregnancy newsletter!

Increase Iron Intake

Being diagnosed with an iron deficiency is a real worry for some pregnant moms-to-be and their doctors. This is especially true in India where women are already not getting enough iron in their diets. Known as the top cause of maternal deaths in India, the increase of anemic women and children could be due to the high rate of poverty throughout the country, the caste system still in place in some cultures and poor sanitation.

Iron is critical to a healthy pregnancy. If your find out your iron levels are low during pregnancy, your doctor will encourage you to eat more foods rich in iron. If you’re levels are still low, your doctor may recommend a supplement to bridge the gap and keep you and your baby healthy!

Decrease Consumption of Foods that Raise Body Temperature

Because of fluctuating hormones, a woman’s body temperature often rises during pregnancy. A sudden increase in body temperature can be harmful to a developing fetus. To avoid this, you should increase your intake of foods known to decrease your body’s temperature. This is especially good during the summer months, when the heat in India can cause multiple problems for a woman carrying a child.

Coconut water is known to cool the body, as well as watermelon, amla and fenugreek seeds. Additionally, women should be drinking substantial amounts of water throughout their pregnancy to stay hydrated and cool.

Avoid Pollutants and Toxins

India’s pollution levels can be a cause for concern for pregnant moms. Exposure to too much air pollution can restrict your baby’s growth or cause birth defects. It is important to be proactive and take steps to protect yourself and your baby.

You should avoid areas with heavy amounts of pollutants – or heavy traffic. It is also a good idea to wear a mask to filter our harmful toxins when you must go outdoors, and to invest in an air purifier to make sure your home is as pollutant-free as possible!

Want the latest pregnancy tips and info? Subscribe to our pregnancy newsletter!

Work Safely

While you should always consult your doctor first, there is no reason that you cannot continue to work if your pregnancy is healthy and considered low risk. Working can be beneficial for a pregnant woman – it keeps them active and focused on a normal routine. However, be sure you are working safely if you are pregnant – do not expose yourself to hazardous substances or excessive physical activity.

work safely during pregnancy

Another tip to consider is to work comfortably – wear supportive shoes and invest in a new chair or add a cushion to keep back aches at bay. You also should be sure to stay hydrated and take frequent breaks to avoid overexerting yourself.

Fast Safely

Though research has been conducted, there is still no clear answer on whether or not women should fast during their pregnancy. However, if you do decide to fast after consulting with your doctor, make sure you make it as safe for you and your developing baby as possible. Be sure to take extra precautions if your fast falls during the summer months when the weather is much hotter and you’re at a greater risk for dehydration.

Another tip to consider when fasting during your pregnancy is to make sure you consume enough food between dusk and dawn to sustain you throughout the day. Losing weight is not recommended for pregnant women. You can also consider alternative options to fasting every day, including participating in the fast on the first and last day of the fasting period or taking a break for a day in between fasts.

Don’t be Afraid to Seek Medical Advice

In most cases a woman’s pregnancy is regarded as a normal physiological experience. Traditionally, she will not seek medical advice unless there is an obvious issue, which is especially true in the country’s more rural areas. While it is important to respect your religion’s traditions, do not hesitate to seek medical advice should you have any concern or questions.

It is important to be sure that both you and your baby remain healthy from conception to delivery, and sometimes that means going against the norm and seeing a medical professional regularly, and when you have a concern.

Enjoy this Time and Be Selfish

Most importantly, your pregnancy is supposed to be an exciting and happy experience – whether you’re a first-time mom or you’ve been through multiple pregnancies. Enjoy every minute of it – even the not so great parts like swollen feet and morning sickness. Take pride in the fact that you are growing a human being inside you and what your body is capable of during this time.

 

healthy pregnancy

This is also a time in your life when you can be a little selfish – I mean you are sharing your body with another person, you may need a little extra help or some more time for yourself. Sleep in if you need to, don’t be afraid to ask your partner and family for help and remember to enjoy your pregnancy!

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NIPT: Detect Chromosomal Conditions with Greater Accuracy https://medgenomeclaria.com/2017/07/19/nipt-detect-chromosomal-conditions-greater-accuracy/ https://medgenomeclaria.com/2017/07/19/nipt-detect-chromosomal-conditions-greater-accuracy/#respond Wed, 19 Jul 2017 19:17:34 +0000 https://www.medgenomeclaria.com/?p=29153 Every year around 1.7 million babies are born with a birth defect in India. Some of the most common disorders diagnosed throughout the country are chromosomal conditions like Down syndrome, Edward’s syndrome or Patau syndrome – which effect the physical, mental and emotional development of your baby. The commonality of these defects can be attributed to a number of different factors, including consanguineous marriage, limited access to preventative education and resources, pollution, genetics and the mother’s health and age.

With such an alarming rate of chromosomal conditions across the nation, but especially in the country’s most rural areas, programs have been implemented to address the issue and reduce the number of babies born with these disorders. Geneticists and medical practitioners have been searching for new methods to lessen India’s burden of birth defects, providing more options for India couples wanting to start a healthy family.

Prenatal screening is becoming a popular procedure to ease the minds of parents-to-be about their babies’ health, with no associated risks to the mother or baby. All pregnant women can get screened to determine the risk of their babies being born with a chromosomal condition as early as nine weeks into their pregnancy. Our Non-Invasive Prenatal Test, referred to commonly as NIPT, is 99.9% accurate, can help screen for some of these common conditions and can be completed with just a simple blood test.

What is a Chromosomal Condition?

In most cases, babies have a total of 46 chromosomes, the thread-like structures which hold our genes and determine our traits. Twenty-three of the chromosomes are received from the baby’s mother and the other 23 from the baby’s father. However, in some circumstances a baby may be born with an extra, missing or defective chromosome, which can result in your baby developing a chromosomal condition.

Common Chromosomal Conditions NIPT Screens For

Down Syndrome

The most common chromosomal condition is Down syndrome, also known as trisomy 21. Babies born with Down syndrome have an extra copy of chromosome 21 which alters the development of their body and brain. According to the Down Syndrome Federation of India, Down syndrome occurs in approximately 1 of 830 live births. Babies born with Down syndrome have distinct physical characteristics and often experience developmental delays, low muscle tone and learning disabilities. In addition, those diagnosed with Down syndrome are also at risk for associated health issues like heart defects, hearing loss or thyroid problems.

Unfortunately, trisomy 21 cannot be prevented. It can, however, be detected before the baby is born – giving families plenty of time to prepare, and do research on the condition and resources available to them. It is recommended all pregnant women screen for Down syndrome with the NIPT, but is especially recommended for mothers over 35 or for mothers who already have a child with the condition.

Edwards Syndrome

Also known as trisomy 18, Edwards syndrome occurs when a baby has a partial or full copy of chromosome 18. This chromosomal condition occurs in about 1 in every 6,000 live births. Most babies diagnosed with trisomy 18 will not survive to full term because of the life-threatening problems associated with the condition.

Babies with Edwards syndrome normally have a slow growth rate, low birth weight, an abnormally-shaped head, small jaw and extreme delays in their intellectual development. In addition, they may have kidney defects, heart problems, protruding intestines and difficulties with breathing and eating. Babies that do survive birth have only a 5-25% chance of surviving their first year of life.

Edwards syndrome, which was named after John Hilton Edwards who first described the condition, is not normally inherited but it can be detected with prenatal screening. If common characteristics for the disorder are detected, a diagnosis can be confirmed with further testing.

Patau Syndrome

Another chromosomal condition that can be detected with prenatal testing is trisomy 13, commonly referred to as Patau syndrome. This rare but serious condition occurs when a baby has three copies of chromosome 13 instead of two. Patau syndrome occurs is about 1 in every 16,000 live births and is characterized by severe development delays and advanced organ defects.

Most babies diagnosed with Patau syndrome will not survive the first few days or week of life due to a host of complications from associated medical problems. Babies that do survive to full term and delivery often have heart defects, brain and spinal cord abnormalities, structural eye defects, cleft palate and kidney problems.

There is no treatment for Patau syndrome and any management of the condition focuses on the physical problem associated with it.

After the Results

You will receive your NIPT results within 7-10 days after the procedure. A genetic counsellor can review your results with you and answer any questions. If the NIPT does detect an abnormality, the next step will be a diagnostic test, such as a CVS or amniocentesis, to confirm the findings and provide a diagnosis.

The earlier a chromosomal condition is detected, the more time you have to research and implement any available treatment options, as well as prepare for any care your baby will require after birth.

When you’re expecting, you need clear answers about your baby’s health. Ask your doctor about how you can get prenatal screening for chromosomal conditions, or contact us at 1800-103-7590.

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9 Important Tips You Should Know Before You Conceive a Baby https://medgenomeclaria.com/2017/05/25/9-important-tips-know-conceive-baby/ https://medgenomeclaria.com/2017/05/25/9-important-tips-know-conceive-baby/#respond Thu, 25 May 2017 20:26:57 +0000 https://www.medgenomeclaria.com/?p=29003 If you’re actively trying to conceive a baby with your partner, there are a few lifestyle changes you should make to ensure both you and your baby are healthy. From medications to your diet, here is everything you need to know about experiencing a healthy pregnancy, even before you conceive.

Know When You’re Ovulating

For women wanting to get pregnant, you first need to know when you’re ovulating. During ovulation, the ovary releases a matured egg that is pushed down to the Fallopian tube to get fertilized by sperm, making it the time women are the most fertile and most likely to conceive.

Women ovulate two weeks before their next period and, according to doctors, are likely to get pregnant five days prior to ovulation. Keeping track of your cycles and ovulation can be tricky with a busy lifestyle. Make sure to take advantage of helpful resources like menstrual calendars and ovulation calculators to be sure you’re trying to conceive when you’re the most fertile.

Complete a Pre-Pregnancy Check-Up

A healthy pregnancy starts with making sure both partners are in good health to have a baby. Before you conceive, you and your partner should see your doctors for a pre-pregnancy check-up. This gives you both the chance to get your questions answered by a trained medical professional, and as well as the opportunity to make sure you are both physically and emotionally ready to conceive a baby.

At the appointment, you doctor will complete a full physical exam and will check your medical history to make sure there is nothing that could affect your pregnancy. The genetic history of both partners and families will also be examined to reduce the risk of passing a chromosomal condition to your baby. If there is a cause for concern in your history, your doctor may recommend a carrier screening test to determine exactly your risk of passing a genetic disease to your baby.

Increase Intake of Iron-Rich Foods

Anemia, a condition caused by an iron deficiency, is a common problem among Indian women. In fact, India is home to the highest number of anemic women in the world. It is suggested this is because of increased rates of poverty, malnutrition, poor sanitation and an imbalanced diet throughout the country. It has also been found that anemia is the top cause of maternal deaths in India – making it a major cause for concern for anyone who is pregnant or is thinking about conceiving.

To prevent becoming anemic, be sure you diet includes food rich in iron. Increase your consumption of meat, raisins, prunes, beans and spinach to fortify your iron levels and reduce developing this condition.

Check Your Meds

The medications you are taking could have a major impact on the health of you baby. Some aren’t “baby-friendly” and could cause birth defects. In addition, pregnant women are not normally included in drug studies, meaning we have little to no research on how a medication will affect you or your baby during pregnancy.

Avoid any unnecessary health risk by discussing any current medication you are taking with your doctor. This includes prescriptions, over the counter meds, vitamins and supplements. Be sure you are only taking medications that are absolutely necessary for your health. Your doctor can also prescribe a baby-friendly alternative meds if need be.

Add Fertility-Boosting Foods to Your Diet

Infertility is becoming an issue for a lot of Indian couples. Stress, caffeine intake, smoking and your age can all affect how long it takes you to conceive. Recent trends, including a spike in working hours and a tendency to wait longer to get married, have contributed to an increase in infertility in both Indian men and women.

While there are some things you need to avoid to boost your fertility, there are certain foods you can add to your diet to increase the chances of conceiving.  This includes leafy greens, whole grains, eggs, legumes, meat, and lots and lots of water.

Protect Yourself from Air Pollution

Throughout India, we are dealing with air pollution and its effects on the population. Pregnant women living in areas with high pollution levels need to be proactive to protect themselves and their babies from the long-term consequences unclean air can have. Studies have shown extreme air pollution can result in preterm delivery, low birthweight and irregular brain development.

While you can’t avoid all pollution, you can take a few steps to minimize your exposure. Avoid early morning walks when pollution levels are at their highest, wear a mask to filter pollutants when you must go outside and invest in an air purifier to reduce the risk in your home.

Consider Carrier Screening

With genetic diseases being so widespread throughout India, you may want to consider a carrier screening test – especially if you suffer from a genetic condition or have a family history of one. These DNA screening tests were developed to determine if you or your partner carry any genetic disorders that could affect your baby’s health or be passed on to your baby.

With a simple blood test, carrier screening can detect diseases specific to the Indian population. Once you receive your results, a certified genetic counselor can help you understand your options and help you decide the next step.

Develop a Support System

Even the healthiest people can take more time than planned to conceive a baby. There are many factors that go into a successful pregnancy, which means you may not get pregnant right away. This is completely normal but there is still a stigma when it comes to infertility in married, Indian women. The stress of not getting pregnant right after marriage could affect your overall health and slow down your chances of conceiving.

To combat this, make sure you have a support system in place that you can turn to when you’re feeling overwhelmed and unsure. This could be a family member or friend, or even your doctor. Don’t let the stigma of not getting pregnant right away affect your chances down the road.

Check Something off Your Bucket List

Before your life is consumed with doctor appointments, baby showers and preparing your home for your newest arrival, be sure you and your partner take some time for yourselves. Your lives and priorities will drastically change the moment you find out you’re pregnant, and even more so once you deliver, so there is no better time to check something off your bucket list than pre-conception .

Take a trip, add an addition to your house, or get a new puppy. Trust me, it is so much harder to accomplish anything when you’ve got what feels like a 20 lb. watermelon growing under your shirt.

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An Introduction to Down Syndrome – The Most Common Chromosomal Disorder in the World https://medgenomeclaria.com/2017/04/17/down-syndrome-the-most-common-chromosomal-disorder-in-the-world/ https://medgenomeclaria.com/2017/04/17/down-syndrome-the-most-common-chromosomal-disorder-in-the-world/#respond Mon, 17 Apr 2017 07:03:16 +0000 http://claria.medgenome.wpengine.com/?p=28813 What is Down Syndrome, and What Causes It?

Down syndrome is a chromosomal abnormality that leads to a wide range of developmental delays and physical disabilities in a person. It is one of the most common chromosomal disorders, with an estimated incidence of 1 in 1000 live births worldwide. Every year in India, between 23,000 and 29,000 children are born with Down syndrome, which is the highest in the world.

In most cases, Down Syndrome is caused by an error in cell division, that results in an extra copy of chromosome 21. Having this extra copy changes the brain’s and body’s normal development. To date, there is no evidence of parents’ behaviour or environmental factors increasing or decreasing the chances of having a child with down syndrome.

Types of Down Syndrome

There are three types of chromosomal abnormalities seen in Down syndrome – Trisomy 21, Translocation and Mosaicism.

Trisomy 21, the most common type of Down syndrome, occurs when there are three number 21 chromosomes, instead of the usual two. As the embryo develops, the extra chromosome is replicated in every cell of the body. This additional genetic material alters the course of development and causes the characteristics associated with the syndrome. Trisomy 21 accounts for 95% of cases.

Translocation occurs when part of chromosome 21 breaks off during cell division and attaches to another chromosome in a cell. The total chromosomes in the cells remain 46, but the presence of an extra part of chromosome 21 causes the characteristics of Down syndrome. Translocation accounts for 2-4% of all cases of Down syndrome.

Mosaicism is the least common type of Down syndrome, accounting for only about 1% of all cases. In these cases, some but not all cells have an extra copy of chromosome 21. The symptoms of mosaicism Down syndrome tend to be milder and less wide ranging compared with the other types.

What are the Risk Factors for Down Syndrome?

Maternal age is the most significant factor in increasing the risk for having a child with Down syndrome. A woman who is 30-34 years of age has a risk of 1 in 800, and the likelihood continues to increase as she ages. However, due to higher birth rates in younger women, 80% of children with Down syndrome are born to women under 35 years of age.

Parents who already have a child with Down syndrome, or who are carriers of the genetic translocation of Down syndrome are also at a higher risk of having a child with Down syndrome. Both men and women can pass the abnormal chromosomes for Down syndrome on to their children.

What are the Health Conditions Associated with Down Syndrome?

Everyone born with Down’s syndrome will have a degree of learning disability, but the level of disability will be different for each individual. They have delayed language development and slow motor development. They also have varying degrees of mental and social development delays, which means that the child could have impulsive behaviour, poor judgment, short attention spans and slow learning capabilities.

An infant with Down syndrome can be born at normal size but will develop more slowly than a child without the condition. At birth, babies with Down syndrome usually have certain characteristic signs, including flat facial features, poor muscle tone, eyes that slant upwards and a short neck.

Medical complications often accompany Down syndrome. The may include congenital heart defects, hearing loss, poor vision, hypothyroidism, sleep apnea and obesity. They may also struggle with respiratory infections, urinary tract infections, and skin infections.

Prognosis & Treatment

There is no cure for Down syndrome, but there is a wide variety of support and educational programs that can help both, people with the condition and their families. People with Down syndrome can achieve optimal quality of life through parental care and support, behavioural training, speech therapy, physical therapy and community based support systems like special schools.

How Is Down Syndrome Diagnosed?

Non-invasive prenatal screening is currently the safest option to identify the risk of having a child with Down syndrome. A simple blood test can help screen for the genetic condition from as early as the 9th week of pregnancy. MedGenome Claria provides a safe, non-invasive and highly accurate screening test for expectant parents.

A diagnostic test such as Amniocentesis can be taken to conclusively identify if a baby has Down syndrome. However, unlike NIPT, diagnostic tests such as Amniocentesis carry various risks.

A genetic counselling session can give you clarity and reassurance at a time when you need it the most. Speak to one of our genetic experts to get answers to all your questions, absolutely free of cost.

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